Give differences: Haemophilia and Sickle-cell | vedclass

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(N/A)       Haemophilia    Sickle-cell Anaemia        $(1)$ It occurs due to a defective recessive allele present on the $X$-chromosome.    $(1)$ It o

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(N/A)       Haemophilia    Sickle-cell Anaemia        $(1)$ It occurs due to a defective recessive allele present on the $X$-chromosome.    $(1)$ It occurs due to point mutation,i.e.,a single base pair change leads to a change in amino acid.        $(2)$ The defective allele produces a non-functional protein involved in the blood clotting cascade.    $(2)$ In this,glutamic acid $(Glu)$ is replaced by valine $(Val)$ at the sixth position of the beta-globin chain of the haemoglobin molecule.        $(3)$ It is a sex-linked recessive disorder.    $(3)$ It is an autosomal-linked recessive disorder.        $(4)$ More males are affected than females.    $(4)$ Both males and females are affected equally.

Give differences: Haemophilia and Sickle-cell Anaemia.

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Haemophilia	Sickle-cell Anaemia
$(1)$ It occurs due to a defective recessive allele present on the $X$-chromosome.	$(1)$ It occurs due to point mutation,i.e.,a single base pair change leads to a change in amino acid.
$(2)$ The defective allele produces a non-functional protein involved in the blood clotting cascade.	$(2)$ In this,glutamic acid $(Glu)$ is replaced by valine $(Val)$ at the sixth position of the beta-globin chain of the haemoglobin molecule.
$(3)$ It is a sex-linked recessive disorder.	$(3)$ It is an autosomal-linked recessive disorder.
$(4)$ More males are affected than females.	$(4)$ Both males and females are affected equally.